Advanced micro-depositing technology that enables precise, systemic delivery of potent compounds through the mucosal tissue. The first FDA-approved non-matrix thin film, MicroDEP delivers unparalleled precision, efficiency, and bioavailability for buccal and sublingual applications.
Highest Mucosal Thin Film Bioavailability Approved by the FDA
FDA-Approved, GRAS-Compliant Materials
Scalable Production with Uniformity Controls
MicroDEP uses advanced technology to deposit small, precise formulations of API directly on the surface of the thin film. Ths method provides optimal use of the API, ensuring efficient and effective drug delivery.
Place inside the cheek or under the tongue.
The film dissolves, releasing the drug through the mucosal tissue into the bloodstream.
Rapid onset and optimal therapeutic results via enhanced bioavailability.
MicroDEP films deliver precise and reliable results in a convenient format.
ARx can support your development journey end-to-end, from feasibility studies to full-scale production. Explore how our team can help you ensure a reliable, high-quality end product.
We provide a range of alternative drug delivery systems, including lingual, buccal and sublingual thin films, and transdermal and topical patches. All customizable to meet your specific needs.
MicroDEP thin films are highly versatile and can deliver a variety of APIs, including biologics, specialty drugs, and precision therapeutics. They are especially effective for drugs needing rapid absorption, localized delivery, or advanced controlled release mechanisms.
A specialized API delivery method, like MicroDEP, can improve how effectively your drug works, making it easier for patients to take and set your product apart in the market. It allows for better bioavailability, tailored dosing, and solutions for specific patient needs, like those who have trouble swallowing pills.
Depending on solubility, stability, and absorption needs, most drugs can be delivered using MicroDEP thin films. A feasibility study can confirm if this format is right for your API, and formulation advancements make it possible to adapt many challenging APIs.
MicroDEP thin films dissolve within 5 to 30 seconds, depending on their formulation. This rapid dissolution ensures immediate drug release for quick therapeutic effects.
MicroDEP offers several key benefits compared to tablets and capsules:
Yes, MicroDEP thin films can significantly enhance patient compliance. They are discreet, easy to use, don’t require swallowing, and can be formulated with taste-masking technology to improve the flavor of bitter drugs.
MicroDEP can accommodate many APIs, including those with solubility or bioavailability challenges. The films can be designed with single or multi-layer systems to protect sensitive APIs while ensuring efficient absorption. APIs suited for buccal, sublingual, or systemic delivery are ideal for this format.
MicroDEP enhances bioavailability by delivering precise drug deposits directly to the absorption site. This minimizes first-pass metabolism, allowing for faster and more efficient absorption. The polymer used in MicroDEP ensures stability, flexibility, and optimal drug release, creating a thin film of the drug that is readily accessible for maximum effectiveness.
MicroDEP thin films comprise GRAS excipients, such as film-forming polymers, plasticizers, and stabilizers. These ensure film stability and compatibility with a wide range of APIs.
Yes, MicroDEP allows extensive customization, including tailored release profiles, multi-layer systems, and formulations for diverse patient populations—such as pediatrics and geriatrics.
The development process follows all QbD and FDA regulations, including feasibility studies, formulation optimization, analytical and QC testing, process development, and cGMP manufacture.
MicroDEP thin films are designed for long-term stability, packaged in a foil pouch with protection from light and moisture. Customized stability protocols ensure product safety and efficacy.
Discover how MicroDEP transforms therapeutic outcomes through precision and innovation. With a legacy of expertise in drug delivery, ARx collaborates with clients to develop cutting-edge advancements, including MicroDEP, that meet specific therapeutic needs.
